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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NFkB p100 / p52 Polyclonal Antibody

NFkB p100 / p52 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25127N-1 50ul / $395
APR25127N-2 100ul / $495
APR25127N-3 200ul / $595

NFkB p100 / p52 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25127N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NFkB p100 / p52 Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa/96kDa Observed MW: 110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NFkB p100 / p52 (NP_002493.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Synonyms

NFKB2; CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52; nuclear factor kappa B subunit 2

Images

Western blot analysis of extracts of various cell lines, using NFkB p100 / p52 antibody.

Immunohistochemistry of paraffin-embedded rat brain using NFkB p100 / p52 antibody.

Immunohistochemistry of paraffin-embedded human breast using NFkB p100 / p52 antibody.

Specification

Quantity

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