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SPAG6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25114N-1 50ul / $395
APR25114N-2 100ul / $495
APR25114N-3 200ul / $595

SPAG6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25114N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPAG6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa/49kDa/52kDa/55kDa/63kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SPAG6 (NP_758442.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

SPAG6; CT141; Repro-SA-1; pf16; sperm-associated antigen 6

Images

Western blot analysis of extracts of various cell lines, using SPAG6 antibody.

Specification

Quantity

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