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PDX1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25104N-1 50ul / $395
APR25104N-2 100ul / $495
APR25104N-3 200ul / $595

PDX1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25104N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Endocrine and metabolic diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDX1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa Observed MW: 34kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human PDX1

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Synonyms

PDX1; GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1; pancreatic and duodenal homeobox 1

Images

Western blot analysis of extracts of mouse intestine, using PDX1 antibody.

Specification

Quantity

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