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NFASC Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25093N-1 50ul / $395
APR25093N-2 100ul / $495
APR25093N-3 200ul / $595

NFASC Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25093N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NFASC Polyclonal Antibody.

Molecular Weight

Calculated MW: 69kDa/119kDa/130-150kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NFASC (NP_001005388.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.

Synonyms

NFASC; NF; NRCAML; neurofascin

Images

Western blot analysis of extracts of various cell lines, using NFASC antibody.

Specification

Quantity

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