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NPHS1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25091N-1 50ul / $395
APR25091N-2 100ul / $495
APR25091N-3 200ul / $595

NPHS1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25091N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NPHS1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 130kDa/134kDa Observed MW: 130kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human NPHS1

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Product Description

This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

Synonyms

NPHS1; CNF; NPHN; nephrin

Images

Western blot analysis of extracts of mouse kidney, using NPHS1 antibody.

Western blot analysis of extracts of various cell lines, using NPHS1 antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using NPHS1 antibody.

Specification

Quantity

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