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KCNA1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25062N-1 50ul / $395
APR25062N-2 100ul / $495
APR25062N-3 200ul / $595

KCNA1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25062N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNA1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa Observed MW: 56kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human KCNA1

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Synonyms

KCNA1; AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1; potassium voltage-gated channel subfamily A member 1

Images

Western blot analysis of extracts of U-251MG cells, using KCNA1 antibody.

Specification

Quantity

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