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GRM1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25043N-1 50ul / $395
APR25043N-2 100ul / $495
APR25043N-3 200ul / $595

GRM1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25043N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRM1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 101kDa/132kDa Observed MW: 132kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human GRM1

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

GRM1; GPRC1A; MGLU1; MGLUR1; PPP1R85; SCAR13; metabotropic glutamate receptor 1

Images

Western blot analysis of extracts of mouse brain, using GRM1 antibody.

Specification

Quantity

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