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EPOR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25020N-1 50ul / $395
APR25020N-2 100ul / $495
APR25020N-3 200ul / $595

EPOR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25020N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EPOR Polyclonal Antibody.

Molecular Weight

Calculated MW: 26kDa/35kDa/55kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human EPOR (NP_000112.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Synonyms

EPOR; EPO-R; erythropoietin receptor

Images

Western blot analysis of extracts of various cell lines, using EPOR antibody.

Immunohistochemistry of paraffin-embedded human prostate using EPOR antibody.

Immunohistochemistry of paraffin-embedded human trachea using EPOR antibody.

Specification

Quantity

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