> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > EPOR Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR25020N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cardiovascular>Angiogenesis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EPOR Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
26kDa/35kDa/55kDa
Observed MW:
55kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human EPOR (NP_000112.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
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Product Description |
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
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Synonyms |
EPOR; EPO-R; erythropoietin receptor
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Images |
Western blot analysis of extracts of various cell lines, using EPOR antibody.
Immunohistochemistry of paraffin-embedded human prostate using EPOR antibody.
Immunohistochemistry of paraffin-embedded human trachea using EPOR antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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