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EDNRB Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25013N-1 50ul / $395
APR25013N-2 100ul / $495
APR25013N-3 200ul / $595

EDNRB Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25013N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EDNRB Polyclonal Antibody.

Molecular Weight

Calculated MW: 48kDa/49kDa/59kDa Observed MW: 49kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human EDNRB (NP_001116131.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Synonyms

EDNRB; ABCDS; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A; endothelin B receptor

Images

Western blot analysis of extracts of various cell lines, using EDNRB antibody.

Specification

Quantity

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