> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > EIF4G2 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR25005N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Apoptosis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EIF4G2 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
98kDa/102kDa
Observed MW:
102kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic peptide of human EIF4G2 (NP_001409.3).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:1000
IHC 1:100 - 1:200
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Product Description |
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
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Synonyms |
EIF4G2; AAG1; DAP5; NAT1; P97; eukaryotic translation initiation factor 4 gamma 2
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Images |
Western blot analysis of extracts of various cell lines, using EIF4G2 antibody.
Immunohistochemistry of paraffin-embedded human stomach using EIF4G2 antibody.
Immunohistochemistry of paraffin-embedded mouse spleen using EIF4G2 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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