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CLDN19 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24988N-1 50ul / $395
APR24988N-2 100ul / $495
APR24988N-3 200ul / $595

CLDN19 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24988N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN19 Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa/23kDa Observed MW: 23kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CLDN19 (NP_001116867.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms

CLDN19; HOMG5; claudin-19

Images

Western blot analysis of extracts of various cell lines, using CLDN19 Antibody.

Specification

Quantity

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