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ADAMTS5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24974N-1 50ul / $395
APR24974N-2 100ul / $495
APR24974N-3 200ul / $595

ADAMTS5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24974N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADAMTS5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 101kDa Observed MW: 105-115kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human ADAMTS5

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis.

Synonyms

ADAMTS5; ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2; ADAM-TS11; ADAM metallopeptidase with thrombospondin type 1 motif 5

Images

Western blot analysis of extracts of various cell lines, using ADAMTS5 antibody.

Specification

Quantity

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