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ACE Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24962N-1 50ul / $395
APR24962N-2 100ul / $495
APR24962N-3 200ul / $595

ACE Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24962N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACE Polyclonal Antibody.

Molecular Weight

Calculated MW: 78kDa/83kDa/131kDa/149kDa Observed MW: 110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ACE (NP_690043.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Synonyms

ACE; ACE1; CD143; DCP; DCP1; ICH; MVCD3; angiotensin-converting enzyme

Images

Western blot analysis of extracts of various cell lines, using ACE antibody.

Specification

Quantity

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