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PAK4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24951N-1 50ul / $395
APR24951N-2 100ul / $495
APR24951N-3 200ul / $595

PAK4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24951N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAK4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa/48kDa/54kDa/64kDa Observed MW: 64kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human PAK4

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms

PAK4; p21 (RAC1) activated kinase 4

Images

Western blot analysis of extracts of various cell lines, using PAK4 antibody.

Specification

Quantity

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