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CLDN11 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24876N-1 50ul / $395
APR24876N-2 100ul / $495
APR24876N-3 200ul / $595

CLDN11 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24876N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN11 Polyclonal Antibody.

Molecular Weight

Calculated MW: 21kDa Observed MW: 22kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CLDN11 (NP_005593.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:20 - 1:50

Product Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

CLDN11; OSP; OTM; claudin-11

Images

Western blot analysis of extracts of PC-3 cells, using CLDN11 antibody.

Immunofluorescence analysis of U2OS cells using CLDN11 antibody.

Specification

Quantity

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