> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MRE11A Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR24843N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Cell Cycle |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MRE11A Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
77kDa/80kDa/81kDa
Observed MW:
90kDa-100kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human MRE11A (NP_005581.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IF,IP
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Dilution |
WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:100
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Product Description |
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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Synonyms |
MRE11; ATLD; HNGS1; MRE11A; MRE11B; double-strand break repair protein MRE11
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Images |
Western blot analysis of extracts of various cell lines, using MRE11A antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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