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MT1-MMP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24833N-1 50ul / $395
APR24833N-2 100ul / $495
APR24833N-3 200ul / $595

MT1-MMP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24833N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MT1-MMP Polyclonal Antibody.

Molecular Weight

Calculated MW: 65kDa Observed MW: 46-70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human MT1-MMP

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Synonyms

MMP14; MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS; MT-MMP1; matrix metallopeptidase 14

Images

Western blot analysis of extracts of various cell lines, using MT1-MMP antibody.

Immunohistochemistry of paraffin-embedded rat kidney using MT1-MMP antibody.

Immunohistochemistry of paraffin-embedded human kidney using MT1-MMP antibody.

Specification

Quantity

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