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EGLN1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24751N-1 50ul / $395
APR24751N-2 100ul / $495
APR24751N-3 200ul / $595

EGLN1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24751N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EGLN1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 36kDa/43kDa/46kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human EGLN1 (NP_071334.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IF

Dilution

IF 1:50 - 1:200

Product Description

The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

Synonyms

EGLN1; C1orf12; ECYT3; HALAH; HIF-PH2; HIFPH2; HPH-2; HPH2; PHD2; SM20; ZMYND6; egl nine homolog 1

Images

Immunofluorescence analysis of MCF-7 cells using EGLN1 antibody.

Specification

Quantity

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