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OGG1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24744N-1 50ul / $395
APR24744N-2 100ul / $495
APR24744N-3 200ul / $595

OGG1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24744N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OGG1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa/36kDa/38kDa/39kDa/40kDa/45kDa/47kDa Observed MW: 36kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human OGG1

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:1000

Product Description

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.

Synonyms

OGG1; HMMH; HOGG1; MUTM; OGH1; N-glycosylase/DNA lyase

Images

Western blot analysis of extracts of HepG2 cells, using OGG1 antibody.

Specification

Quantity

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