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MBD3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24741N-1 50ul / $395
APR24741N-2 100ul / $495
APR24741N-3 200ul / $595

MBD3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24741N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MBD3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 29kDa/32kDa Observed MW: 36kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MBD3 (NP_001268383.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene.

Synonyms

MBD3; methyl-CpG-binding domain protein 3

Images

Western blot analysis of extracts of various cell lines, using MBD3 antibody.

Specification

Quantity

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