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Claudin 1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24713N-1 50ul / $395
APR24713N-2 100ul / $495
APR24713N-3 200ul / $595

Claudin 1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24713N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Claudin 1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Claudin 1 (NP_066924.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Synonyms

CLDN1; CLD1; ILVASC; SEMP1; claudin-1

Images

Western blot analysis of extracts of SW620 cells, using CLDN1 antibody.

Immunohistochemistry of paraffin-embedded rat kidney using Claudin 1 antibody.

Immunohistochemistry of paraffin-embedded human lung cancer using Claudin 1 antibody.

Specification

Quantity

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