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KCNQ1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24692N-1 50ul / $395
APR24692N-2 100ul / $495
APR24692N-3 200ul / $595

KCNQ1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24692N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Heart

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNQ1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 61kDa/74kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human KCNQ1 (NP_861463.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Synonyms

KCNQ1; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; KVLQT1; Kv1.9; Kv7.1; LQT; LQT1; RWS; SQT2; WRS; potassium voltage-gated channel subfamily Q member 1

Images

Western blot analysis of extracts of various cell lines, using KCNQ1 antibody.

Specification

Quantity

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