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IRF3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24690N-1 50ul / $395
APR24690N-2 100ul / $495
APR24690N-3 200ul / $595

IRF3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24690N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRF3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 12kDa/16kDa/33kDa/47kDa/49kDa Observed MW: 44kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human IRF3

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

IRF3; IIAE7; interferon regulatory factor 3

Images

Western blot analysis of extracts of various cell lines, using IRF3 antibody.

Immunofluorescence analysis of HeLa cells using IRF3 antibody.

Specification

Quantity

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