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CYP2E1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24678N-1 50ul / $395
APR24678N-2 100ul / $495
APR24678N-3 200ul / $595

CYP2E1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24678N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Drug metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP2E1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CYP2E1 (NP_000764.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:20 - 1:100

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Synonyms

CYP2E1; CPE1; CYP2E; P450-J; P450C2E; cytochrome P450 2E1

Images

Western blot analysis of extracts of various cell lines, using CYP2E1 antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using CYP2E1 antibody.

Immunohistochemistry of paraffin-embedded human stomach using CYP2E1 antibody.

Specification

Quantity

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