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MAX Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24675N-1 50ul / $395
APR24675N-2 100ul / $495
APR24675N-3 200ul / $595

MAX Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24675N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>MAPK-P38 Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAX Polyclonal Antibody.

Molecular Weight

Calculated MW: 9kDa/11kDa/12kDa/15kDa/17kDa/18kDa Observed MW: 19kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MAX (NP_002373.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Synonyms

MAX; bHLHd4; protein max

Images

Western blot analysis of extracts of mouse kidney, using MAX antibody.

Immunohistochemistry of paraffin-embedded rat brain using MAX antibody.

Immunohistochemistry of paraffin-embedded mouse brain using MAX antibody.

Specification

Quantity

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