> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HDAC3 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR24657N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Apoptosis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HDAC3 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
48kDa/49kDa
Observed MW:
47kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human HDAC3 (NP_003874.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF,IP,ChIP
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
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Product Description |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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Synonyms |
HDAC3; HD3; RPD3; RPD3-2; histone deacetylase 3
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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