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SMARCA4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24638N-1 50ul / $395
APR24638N-2 100ul / $495
APR24638N-3 200ul / $595

SMARCA4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24638N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMARCA4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 181kDa/184kDa Observed MW: 190kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human SMARCA4 (NP_003063.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

SMARCA4; BAF190; BAF190A; BRG1; CSS4; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2; hSNF2b; transcription activator BRG1

Images

Western blot analysis of extracts of various cell lines, using SMARCA4 antibody.

Immunofluorescence analysis of A549 cells using SMARCA4 antibody.

Specification

Quantity

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