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ITGAV Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24613N-1 50ul / $395
APR24613N-2 100ul / $495
APR24613N-3 200ul / $595

ITGAV Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24613N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGAV Polyclonal Antibody.

Molecular Weight

Calculated MW: 111kDa/112kDa/116kDa Observed MW: 140kDa

Species Reactivity

Rabbit

Immunogen

A synthetic synthetic peptide of human ITGAV (NP_002201.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Synonyms

ITGAV; CD51; MSK8; VNRA; VTNR; integrin alpha-V

Images

Western blot analysis of extracts of various cell lines, using ITGAV antibody.

Immunohistochemistry of paraffin-embedded rat kidney using ITGAV antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using ITGAV antibody.

Specification

Quantity

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