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IL13 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24611N-1 50ul / $395
APR24611N-2 100ul / $495
APR24611N-3 200ul / $595

IL13 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24611N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL13 Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa Observed MW: 16kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IL13 (NP_002179.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Synonyms

IL13; IL-13; P600; interleukin-13

Images

Western blot analysis of extracts of mouse pancreas, using IL13 antibody.

Immunohistochemistry of paraffin-embedded mouse brain using IL13 antibody.

Immunohistochemistry of paraffin-embedded rat brain using IL13 antibody.

Specification

Quantity

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