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CDKN1C Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24586N-1 50ul / $395
APR24586N-2 100ul / $495
APR24586N-3 200ul / $595

CDKN1C Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24586N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDKN1C Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/32kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human CDKN1C (NP_000067.1).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms

CDKN1C; BWCR; BWS; KIP2; WBS; p57; p57Kip2; cyclin-dependent kinase inhibitor 1C

Images

Western blot analysis of extracts of various cell lines, using CDKN1C antibody.

Specification

Quantity

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