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ADRB2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24575N-1 50ul / $395
APR24575N-2 100ul / $495
APR24575N-3 200ul / $595

ADRB2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24575N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADRB2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa Observed MW: 53-65kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ADRB2 (NP_000015.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Synonyms

ADRB2; ADRB2R; ADRBR; B2AR; BAR; BETA2AR; adrenoceptor beta 2

Images

Western blot analysis of extracts of various cell lines, using ADRB2 antibody.

Specification

Quantity

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