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RPL5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24515N-1 50ul / $395
APR24515N-2 100ul / $495
APR24515N-3 200ul / $595

RPL5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24515N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RPL5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 34kDa Observed MW: 37kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RPL5 (NP_000960.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Synonyms

RPL5; DBA6; L5; MSTP030; PPP1R135; ribosomal protein L5

Images

Western blot analysis of extracts of various cell lines, using RPL5 antibody.

Immunohistochemistry of paraffin-embedded mouse liver using RPL5 antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using RPL5 antibody.

Specification

Quantity

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