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Histone H2B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24497N-1 50ul / $395
APR24497N-2 100ul / $495
APR24497N-3 200ul / $595

Histone H2B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24497N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic Modifications

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Histone H2B Polyclonal Antibody.

Molecular Weight

Calculated MW: 13kDa Observed MW: 15kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HIST2H2BE (NP_003519.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

Synonyms

HIST2H2BE; GL105; H2B; H2B.1; H2BFQ; H2BGL105; H2BQ; histone H2B type 2-E

Images

Western blot analysis of extracts of various cell lines, using Histone H2B antibody.

Immunohistochemistry of paraffin-embedded human esophagus using Histone H2B antibody.

Immunohistochemistry of paraffin-embedded rat kidney using Histone H2B antibody.

Specification

Quantity

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