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TNNC1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24469N-1 50ul / $395
APR24469N-2 100ul / $495
APR24469N-3 200ul / $595

TNNC1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24469N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNNC1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 18kDa Observed MW: 16kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TNNC1 (NP_003271.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Synonyms

TNNC1; CMD1Z; CMH13; TN-C; TNC; TNNC; troponin C1, slow skeletal and cardiac type

Images

Western blot analysis of extracts of various cell lines, using TNNC1 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using TNNC1 antibody.

Immunofluorescence analysis of U2OS cells using TNNC1 antibody.

Specification

Quantity

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