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PKLR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24467N-1 50ul / $395
APR24467N-2 100ul / $495
APR24467N-3 200ul / $595

PKLR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24467N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Carbohydrate metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKLR Polyclonal Antibody.

Molecular Weight

Calculated MW: 58kDa/61kDa Observed MW: 62kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PKLR (NP_000289.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

PKLR; PK1; PKL; PKR; PKRL; RPK; pyruvate kinase PKLR

Images

Western blot analysis of extracts of Raji cells, using PKLR antibody.

Immunohistochemistry of paraffin-embedded human normal breast using PKLR antibody.

Immunohistochemistry of paraffin-embedded human normal colon using PKLR antibody.

Specification

Quantity

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