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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] PRDX2 Polyclonal Antibody

[KO Validated] PRDX2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24462N-1 50ul / $395
APR24462N-2 100ul / $495
APR24462N-3 200ul / $595

[KO Validated] PRDX2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24462N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] PRDX2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa/21kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PRDX2 (NP_859428.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Synonyms

PRDX2; HEL-S-2a; NKEF-B; NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA; peroxiredoxin-2

Images

Western blot analysis of extracts of various cell lines, using PRDX2 antibody.

Western blot analysis of extracts from normal (control) and PRDX2 knockout (KO) 293T cells, using PRDX2 antibody.

Immunofluorescence analysis of HeLa cells using PRDX2 antibody.

Specification

Quantity

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