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CNTF Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24458N-1 50ul / $395
APR24458N-2 100ul / $495
APR24458N-3 200ul / $595

CNTF Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24458N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CNTF Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa Observed MW: 26kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CNTF (NP_000605.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Synonyms

CNTF; HCNTF; ciliary neurotrophic factor

Images

Western blot analysis of extracts of mouse muscle, using CNTF antibody.

Specification

Quantity

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