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SFTPC Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24387N-1 50ul / $395
APR24387N-2 100ul / $495
APR24387N-3 200ul / $595

SFTPC Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24387N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Lipids

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SFTPC Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/21kDa Observed MW: 21kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SFTPC (NP_001165881.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Synonyms

SFTPC; BRICD6; PSP-C; SFTP2; SMDP2; SP-C; surfactant protein C

Images

Western blot analysis of extracts of various cell lines, using SFTPC antibody.

Immunohistochemistry of paraffin-embedded human lung using SFTPC antibody.

Immunohistochemistry of paraffin-embedded rat lung using SFTPC antibody.

Specification

Quantity

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