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HNRNPD Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24374N-1 50ul / $395
APR24374N-2 100ul / $495
APR24374N-3 200ul / $595

HNRNPD Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24374N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRNPD Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa/32kDa/36kDa/38kDa Observed MW: 43kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HNRNPD (NP_002129.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.

Synonyms

HNRNPD; AUF1; AUF1A; HNRPD; P37; hnRNPD0; heterogeneous nuclear ribonucleoprotein D

Images

Western blot analysis of extracts of various cell lines, using HNRNPD antibody.

Immunohistochemistry of paraffin-embedded rat lung using HNRNPD Antibody.

Immunohistochemistry of paraffin-embedded human liver using HNRNPD Antibody.

Specification

Quantity

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