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ATP6V1C1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24350N-1 50ul / $395
APR24350N-2 100ul / $495
APR24350N-3 200ul / $595

ATP6V1C1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24350N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP6V1C1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 43kDa Observed MW: 43kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human ATP6V1C1.

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.

Synonyms

VATC; Vma5; ATP6C; ATP6D

Images

Western blot analysis of extracts of various cell lines, using ATP6V1C1 antibody.

Western blot analysis of extracts of Mouse kidney, using ATP6V1C1 antibody.

Specification

Quantity

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