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EIF6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24277N-1 50ul / $395
APR24277N-2 100ul / $495
APR24277N-3 200ul / $595

EIF6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24277N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 23kDa/26kDa Observed MW: 27kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human EIF6 (NP_852133.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Synonyms

EIF6; CAB; EIF3A; ITGB4BP; b(2)gcn; eIF-6; p27(BBP); p27BBP; eukaryotic translation initiation factor 6

Images

Western blot analysis of extracts of various cell lines, using EIF6 antibody.

Immunofluorescence analysis of MCF-7 cells using EIF6 antibody.

Confocal immunofluorescence analysis of Hela cells using EIF6 antibody.

Specification

Quantity

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