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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] BUB1 Polyclonal Antibody

[KO Validated] BUB1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24182N-1 50ul / $395
APR24182N-2 100ul / $495
APR24182N-3 200ul / $595

[KO Validated] BUB1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24182N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] BUB1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 115kDa/120kDa/122kDa Observed MW: 122kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human BUB1 (NP_004327.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Synonyms

BUB1; BUB1A; BUB1L; hBUB1; BUB1 mitotic checkpoint serine/threonine kinase

Images

Western blot analysis of extracts from normal (control) and BUB1 knockout (KO) HeLa cells, using BUB1 antibody.

Specification

Quantity

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