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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] TRIM21 Polyclonal Antibody

[KO Validated] TRIM21 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24165N-1 50ul / $395
APR24165N-2 100ul / $495
APR24165N-3 200ul / $595

[KO Validated] TRIM21 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24165N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] TRIM21 Polyclonal Antibody.

Molecular Weight

Calculated MW: 45kDa/54kDa Observed MW: 54kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TRIM21 (NP_003132.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Synonyms

TRIM21; RNF81; RO52; Ro/SSA; SSA; SSA1; tripartite motif containing 21

Images

Western blot analysis of extracts from normal (control) and TRIM21 knockout (KO) A-549 cells, using TRIM21 antibody.

Specification

Quantity

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