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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] PRDX3 Polyclonal Antibody

[KO Validated] PRDX3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24163N-1 50ul / $395
APR24163N-2 100ul / $495
APR24163N-3 200ul / $595

[KO Validated] PRDX3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24163N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Cardiovascular diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] PRDX3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 25kDa/27kDa Observed MW: 25kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PRDX3 (NP_006784.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

Synonyms

PRDX3; AOP-1; AOP1; HBC189; MER5; PRO1748; SP-22; prx-III; peroxiredoxin 3

Images

Western blot analysis of extracts from normal (control) and PRDX3 knockout (KO) HeLa cells, using PRDX3 antibody.

Specification

Quantity

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