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DCK Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24101N-1 50ul / $395
APR24101N-2 100ul / $495
APR24101N-3 200ul / $595

DCK Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24101N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DCK Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa Observed MW: 31kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DCK (NP_000779.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Synonyms

DCK; deoxycytidine kinase

Images

Western blot analysis of extracts of various cell lines, using DCK Antibody.

Immunohistochemistry of paraffin-embedded rat kidney using DCK antibody.

Immunohistochemistry of paraffin-embedded human gastric cancer using DCK antibody.

Specification

Quantity

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