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PDE3A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24082N-1 50ul / $395
APR24082N-2 100ul / $495
APR24082N-3 200ul / $595

PDE3A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24082N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDE3A Polyclonal Antibody.

Molecular Weight

Calculated MW: 125kDa Observed MW: 125kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PDE3A (NP_000912.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

HTNB; CGI-PDE; CGI-PDE A; CGI-PDE-A

Images

Western blot analysis of extracts of various cell lines, using PDE3A antibody.

Immunofluorescence analysis of HeLa cells using PDE3A Polyclonal Antibody.

Specification

Quantity

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