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CASP6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24036N-1 50ul / $395
APR24036N-2 100ul / $495
APR24036N-3 200ul / $595

CASP6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24036N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa/33kDa Observed MW: 35kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CASP6 (NP_001217.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Synonyms

CASP6; MCH2; caspase-6

Images

Western blot analysis of extracts of mouse liver, using CASP6 Antibody.

Specification

Quantity

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