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POLR2E Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23796N-1 50ul / $395
APR23796N-2 100ul / $495
APR23796N-3 200ul / $595

POLR2E Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23796N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POLR2E Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa Observed MW: 26kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human POLR2E (NP_002686.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Product Description

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms

POLR2E; RPABC1; RPB5; XAP4; hRPB25; hsRPB5; RNA polymerase II subunit E

Images

Western blot analysis of extracts of various cell lines, using POLR2E antibody.

Immunohistochemistry of paraffin-embedded human stomach cancer using POLR2E antibody.

Immunofluorescence analysis of A549 cells using POLR2E antibody.

Specification

Quantity

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