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CD276 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23572N-1 50ul / $395
APR23572N-2 100ul / $495
APR23572N-3 200ul / $595

CD276 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23572N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD276 Polyclonal Antibody.

Molecular Weight

Calculated MW: 33kDa/52kDa/57kDa Observed MW: 120kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human CD276 (NP_001019907.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

CD276; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2; CD276 antigen

Images

Western blot analysis of extracts of U-87MG cells, using CD276 antibody.

Immunohistochemistry of paraffin-embedded human placenta using CD276 antibody.

Immunohistochemistry of paraffin-embedded human tonsil using CD276 antibody.

Specification

Quantity

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