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MMP12 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23521N-1 50ul / $395
APR23521N-2 100ul / $495
APR23521N-3 200ul / $595

MMP12 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23521N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMP12 Polyclonal Antibody.

Molecular Weight

Calculated MW: 54kDa Observed MW: 51kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human MMP12

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:20 - 1:50

Product Description

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.

Synonyms

MMP12; HME; ME; MME; MMP-12; macrophage metalloelastase

Images

Western blot analysis of extracts of human heart, using MMP12 antibody.

Specification

Quantity

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